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FLASH GENE
Symbol LCTL contributors: - updated : 13-10-2005
HGNC name lactase-like
HGNC id 15583
Location 15q22.31      Physical location : 66.840.538 - 66.857.835
Synonym symbol(s) KLG, KLPH
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus  lowly
Skin/Tegumentskin   lowly
Urinarykidney    
Visualeye   lowly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four regions (I-IV) of internal homology
  • an N-terminal signal sequence
  • a glycosidase domain
  • a transmembrane region
  • a short cytoplasmic tail
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Lctl
    Homologene
    FAMILY
  • glycosyl hydrolase 1 family
  • klotho subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    text
  • type I membrane protein
  • brush border
  • perinuclear tubular network structure of the endoplasmic reticulum in cultured cells
  • basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS