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FLASH GENE
Symbol LCR-HBA@ contributors: mct - updated : 29-08-2006
Corresponding disease
ATHAL thalassemia, alpha
Location 16p13      Physical location : -
Genatlas name hemoglobin alpha, 5', locus control region (HS40)
Synonym name alpha locus activating region
Synonym symbol(s) LCRA
DNA
TYPE locus Control Region
SPECIAL FEATURE overlapping, gene in gene
regulatory sequence Binding site
text structure
  • composed of transcription factor binding sites, 3GATA1, 2NFE2 and 1GT/SP1, flanked by an LTR retroposon belonging to the ERV-9 family of human endogenous retroviruses (see MPG-HB-A@)
  • overlapping at least one widely expressed gene C16orf35
    • MAPPING cloned Y linked N status confirmed
    regionally located major located (40kb) in 5' upstream regulatory element of the cluster
    RNA
    TRANSCRIPTS type untranslated
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ATHAL
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS