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FLASH GENE
Symbol LCN8 contributors: mct - updated : 16-10-2023
HGNC name lipocalin 8
HGNC id 27038
Location 9q34.3      Physical location : 139.648.839 - 139.652.731
Synonym name
  • lipocalin 5
  • chromosome 9 open reading frame 137
  • epididymal-specific lipocalin-8
  • Synonym symbol(s) LCN5, C9orf137, EP17
    DNA
    TYPE functioning gene
    STRUCTURE 4.16 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 884 - 152 - 2004 15363845
    7 - 640 - 175 - 2004 15363845
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemmale genital tractepididymis  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • calycin superfamily
  • lipocalin family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • may play an important role for male fertility (Suzuki 2004)
  • LCN6 is a novel lipocalin closely related to LCN8 and these genes are likely products of gene duplication events that predate rodent-primate divergence
  • LCN6, LCN8, LCN9, LCN10 epididymal secretory proteins are likely involved in ADAM3 maturation and acquisition of sperm fertilizing ability
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS