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FLASH GENE
Symbol LCN1 contributors: npt/ - updated : 05-12-2007
HGNC name lipocalin 1 (tear prealbumin)
HGNC id 6525
Location 9q34.3      Physical location : 138.413.285 - 138.418.378
Synonym name
  • lipocalin 1 (protein migrating faster than albumin, tear prealbumin)
  • Von Ebner gland protein
  • tear lipocalin
  • tear prealbumin
  • lipocalin 1-like 2
  • Synonym symbol(s) MGC71975, PMFA, TP, Tlc, VEGP
    DNA
    TYPE functioning gene
    STRUCTURE 5.09 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map cen - D9S1112 - D9S1793 - D9S66 - D9S1818 - D9S23 - D9S31 - LCN1 /D9S1826 - D9S67 - D9S17 - D9S158 - D9S207 - D9S1838 - qter
    Authors Lacazette (97)
    Physical map
    LOC389804 9 LOC389804 LOC392397 9 similar to hypothetical protein FCN2 9q34 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) FCN1 9q34 ficolin (collagen/fibrinogen domain containing) 1 OLFM1 9q34.3 olfactomedin 1 LOC392398 9 similar to ligand-independent activating molecule for estrogen receptor C9orf62 9q34.3 chromosome 9 open reading frame 62 KIAA0649 9q34.3 chromosome 9 open reading frame 62 MGC29761 9q34.3 hypothetical protein MGC29761 MRPS2 9q34 mitochondrial ribosomal protein S2 LCN1 9q34 lipocalin 1 (protein migrating faster than albumin, tear prealbumin) OBP2A 9q34 lipocalin 1 (protein migrating faster than albumin, tear prealbumin) PAEP 9q34.2-q34.3 progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein) LOC138159 9q34.3 beta-lactoglobulin pseudogene GLTDC1 9q34.3 galactosyltransferase family 6 domain containing 1 LOC392399 9 similar to Putative MUP-like lipocalin precursor LOC286220 9q34.3 hypothetical protein LOC286220 KCNT1 9q34.3 potassium channel, subfamily T, member 1 CAMSAP1 9q34.3 calmodulin regulated spectrin-associated protein 1 LOC389805 9 similar to 9530003A05 protein GBDR1 9q34.1-q34.3 similar to 9530003A05 protein BTBD14A 9q34.3 BTB (POZ) domain containing 14A LOC392400 9 similar to F4N2.10 LOC389806 9 hypothetical gene supported by BC009060 LOC389807 9 LOC389807 LOC389808 9 LOC389808
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 786 - 176 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouth    
     salivary gland    
    Respiratoryrespiratory tracttrachea   
    Visualeye    
     eyelacrimal gland   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandular  
    cell lineage
    cell lines
    fluid/secretion nasal mucus
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
  • a single eight-stranded continuously hydrogen-bonded antiparallel beta-barrel which encloses an internal ligand binding site
  • HOMOLOGY
    Homologene
    FAMILY
  • lipophilic ligand carrier protein superfamily
  • lipocalin family
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the transport of hydrophobic ligands
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • constituent of human tear
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS