basic FUNCTION
| potentially involved in a signaling pathway for the organization of the cytoskeleton |
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may play an important role in the organization of focal adhesions with NEBL and ZYX |
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LASP1 and NEBL, are important during early embryo- and fetogenesis and are highly expressed in the central nervous system of the adult |
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NEBL and LASP1 have distinct roles in the actin cytoskeleton |
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role in chondrocyte differentiation during cartilage to bone transition |
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actin-binding, signaling pathway-regulated phosphoprotein that is overexpressed in several cancers |
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is potenbtially a general mediator of CXC chemokine mediated chemotaxis |
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functional role for LASP1 in the progression and metastatic dissemination of medulloblastoma |
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actin-binding protein that is known to regulate cytoskeleton architecture and cell migration |
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recruited in early steps of podosome assembly |
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multidomain protein predominantly localized at focal contacts, where it regulates cytoskeleton dynamics and cell migration |
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plays a significant role in the formation of several malignant tumours |
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actin-binding protein which is overexpressed in many types of cancers and plays important roles in cancer progression |
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may play an important role in the pathogenesis of esophageal squamous cell carcinoma(ESCC) |
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is an actin-binding protein that regulates cytoskeletal dynamics and cell migration |