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FLASH GENE
Symbol LARP1B contributors: npt - updated : 05-08-2010
HGNC name La ribonucleoprotein domain family, member 1B
HGNC id 24704
Location 4q28.2      Physical location : 128.982.502 - 129.132.287
Synonym name
  • LARP2 protein
  • La ribonucleoprotein domain family, member 2
  • la-related protein 1B
  • Synonym symbol(s) FLJ10378, MGC75174, MGC117277, LARP2, DKFZp434K245, DKFZp686E0316, DKFZp686L13217
    DNA
    TYPE functioning gene
    STRUCTURE 149.79 kb     20 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    20 splicing 3979 105 914 - 2010 20430826
  • isoform 1
  • 11 splicing 1819 59 522 - -
  • eleven exons
  • using an alternate splice site in the 3' coding region, reuslting in a frameshift
  • isoform 2 is shorter and has a distinct C-terminus
  • 9 splicing 2718 41 358 - 2010 20430826
  • nine exons
  • using an alternate splice site in the 3' coding region, reuslting in a frmaeshift
  • isoform 3 is shroter and has a distinct C-terminus
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon  
     salivary gland   highly
    Endocrineneuroendocrinepituitary  highly
     parathyroid   highly
    Reproductivefemale systembreastmammary gland  
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • LARP family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may protect the 3' end of newly synthesized small RNAs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS