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FLASH GENE

Symbol

KRTAP12-3

contributors: npt - updated : 21-10-2009

HGNC name	keratin associated protein 12-3
HGNC id	20531

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	21q22.3      Physical location : 46.077.848 - 46.078.257
Synonym name	high sulfur keratin-associated protein 12.3
Synonym symbol(s)	KAP12.3

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster, gene in gene
text	located within introns of TSPEAR/c21orf29 gene, in a cluster of keratin-associated protein genes
STRUCTURE	0.41 kb     1 Exon(s)

regulatory sequence	Promoter
	Binding site   transcription factor
text structure	intronless functioning gene
	binding elements for the ETS, heat shock factor, AML, and HOX families of transcription factors

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_198697 1 - 410 NP_941970 - 96 - -

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Skin/Tegument skin appendages hair bulb

cells

System Cell Pubmed Species Stage Rna symbol Skin/Tegument hair follicle cell

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

several intragenic repeats

HOMOLOGY

Homologene

FAMILY

KRTAP type 12 family

CATEGORY

structural protein

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytoskeleton,intermed filament

basic FUNCTION

formation of a rigid and resistant hair sheath

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

interacts with hair keratins

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS