Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KRTAP12-2 contributors: - updated : 08-09-2005
HGNC name keratin associated protein 12-2
HGNC id 20530
Location 21q22.3      Physical location : 46.086.106 - 46.086.844
Synonym symbol(s) KRTAP12.2, KAP12.2
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text located within introns of c21orf29/TSPEAR gene, in a cluster of keratin-associated protein genes
STRUCTURE 752.00 kb     1 Exon(s)
regulatory sequence Promoter
Binding site   transcription factor
text structure
  • functionong intronless gene
  • binding elements for the ETS, heat shock factor, AML, and HOX families of transcription factors
  • MAPPING cloned Y linked N status provisional
    Map see KRTAP10-10
    Authors Shibuya et al. (03)
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin appendageshairsheathcuticle 
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumenthair follicle cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • several intragenic repeats
  • HOMOLOGY
    Homologene
    FAMILY hihg sulfur keratinassociated proteins 12
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION essential for the formation of a rigid and resistant hair shaft
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts with hair keratins
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS