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FLASH GENE
Symbol KRTAP10-6 contributors: npt - updated : 07-05-2010
HGNC name keratin associated protein 10-6
HGNC id 20523
Location 21q22.3      Physical location : 46.011.149 - 46.012.386
Synonym name
  • keratin associated protein 18-6
  • high sulfur keratin-associated protein 10.6
  • Synonym symbol(s) KRTAP18-6, KAP10.6, KAP18.6
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster, gene in gene
    text located within introns of TSPEAR/c21orf29 gene, in a cluster of keratin-associated protein genes
    STRUCTURE 1.24 kb     1 Exon(s)
    regulatory sequence Binding site   transcription factor
    text structure
  • functioning intronless gene
  • binding elements for the ETS, heat shock factor, AML, and HOX families of transcription factors
  • MAPPING cloned Y linked N status provisional
    Map see KRTAP10-10
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1238 - 365 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin appendageshairbulb  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumenthair follicle cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • several intragenic repeats
  • HOMOLOGY
    Homologene
    FAMILY
  • KRTAP type 10 family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • formation of a rigid and resistant hair shaft
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with hair keratins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS