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FLASH GENE
Symbol KRTAP10-12 contributors: - updated : 08-09-2005
HGNC name keratin associated protein 10-12
HGNC id 20533
Location 21q22.3      Physical location : 46.117.086 - 46.117.959
Synonym symbol(s) KRTAP18-12, KAP10.12
DNA
TYPE functioning gene
SPECIAL FEATURE
text located within introns of c21orf29/TSPEAR, in a cluster of keratin-associated protein genes
STRUCTURE 873.00 kb     1 Exon(s)
text structure
  • intronless gene
  • binding elements for the ETS, heat shock factor, AML, and HOX families of transcription factors
  • MAPPING cloned Y linked N status provisional
    Map see KRTAP10-10
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin appendageshairbulb  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumenthair follicle cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • several intragenic repeats
  • HOMOLOGY
    Homologene
    FAMILY high sulfur keratin associated proteins 10/18
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION formation of a rigid and resistant hair
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with hair keratins
  • cell & other
    REGULATION
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS