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FLASH GENE
Symbol KRT84 contributors: mct/npt - updated : 30/10/2008
HGNC name keratin 84
HGNC id 6461
Location 12q13      Physical location : 52.771.595 - 52.779.417
Synonym name
  • hair keratin, type II
  • keratin, hair, basic, 4
  • hard keratin, type II, 3
  • hard keratin, type II, 4
  • keratin type II cuticular Hb4
  • Synonym symbol(s) HB4, KRTHB4, K84
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 7.82 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    regionally located clustered with other basic keratins in a domain flanked by type II epithelial keratins, subcluster 2 (with KRT82, KRT85)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 2073 64.9 600 - Schweizer (2006)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue  highly
    Skin/Tegumentskin appendageshairfollicle  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    mono polymer heteromer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • intermediate filament family
  • type II keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • structural constituent of epidermis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimerizes with type I keratins to form hair and nails
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS