Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KRT76 contributors: mct/npt - updated : 30/10/2008
HGNC name keratin 76
HGNC id 24430
Location 12q13.13      Physical location : 53.161.939 - 53.171.129
Synonym name
  • cytokeratin 2
  • keratin 2p
  • keratin, type II cytoskeletal 2 oral
  • Synonym symbol(s) HUMCYT2A, KRT2B, KRT2P, K2P
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text keratin clusters on chromosomes 12 (type II)
    STRUCTURE 9.20 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 2512 65.7 638 - Schweizer (2006)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
     mouth   highly
    Respiratoryrespiratory tractlarynx  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialbarrier liningepidermisstratum basale 
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumentepithelial cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , tetramer
    HOMOLOGY
    interspecies homolog to murine Krt76
    Homologene
    FAMILY
  • intermediate filament family
  • type II keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • major cytoskeletal protein, having structural molecule activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterotetramer of two type I and two type II keratins, keratin 8 associates with keratin 18
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS