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FLASH GENE
Symbol KRT25 contributors: mct/npt - updated : 02-10-2006
HGNC name keratin 25
HGNC id 30839
Location 17q21.2      Physical location : 38.904.273 - 38.911.584
Synonym name
  • type I inner root sheath specific keratin 25 irs1
  • keratin 25A
  • cytokeratin-25
  • keratin, type I cytoskeletal 25
  • Synonym symbol(s) KRT25A, K25irs1
    DNA
    TYPE functioning gene
    STRUCTURE 7.30 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1684 49.3 450 - Schweizer (2006)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumenthair follicle cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to chimpanzee KRT25 (98.7pc)
    homolog to murine Krt25 (91.9pc)
    homolog to rattus Krt25A (90.8pc)
    Homologene
    FAMILY
  • intermediate filament family
  • type I keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION represent the type I inner root sheath keratins of the hair follicle
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS