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FLASH GENE
Symbol KRT20 contributors: mct/npt - updated : 20-04-2004
HGNC name keratin 20
HGNC id 20412
Location 17q21.2      Physical location : 39.032.140 - 39.041.495
Synonym name
  • cytokeratin 20
  • keratin, type I cytoskeletal 20
  • protein IT
  • Synonym symbol(s) K20, CK20, KRT21, MGC35423
    DNA
    TYPE functioning gene
    STRUCTURE 9.28 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    KRT25B 17q21.2 keratin 25B KRT25A 17q21.2 keratin 25A KRT25C 17q21.2 keratin 25C KRT25D 17q21.2 keratin 25C MGC21518 17q21.2 hypothetical protein MGC21518 KRT12 17q21.1 keratin 12 (Meesmann corneal dystrophy) KRT20 17q21.2 keratin 20 KRT23 17q21.2 keratin 23 (histone deacetylase inducible) LOC390792 17 similar to type I hair keratin 6 FLJ36600 17q21.2-q21.31 hypothetical protein FLJ36600 KRTAP3-3 17q12-q21 keratin associated protein 3-3 KRTAP3-2 17q12-q21 keratin associated protein 3-2 KRTAP3P1 17q12-q21 keratin associated protein 3 pseudogene 1 KRTAP3-1 17q12-q21 keratin associated protein 3-1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1817 48.5 424 - Rogers (2001)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon  
     stomach    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialabsorptive excretorydigestive epithelium  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Digestiveenterocyte
    Digestivegastric
    cell lineage
    cell lines colon tumor
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a rod domain
  • mono polymer heteromer , tetramer , complex
    HOMOLOGY
    Homologene
    FAMILY
  • intermediate filament family
  • type I keratin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • responsible for the structural integrity of epithelial cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other K20 Ser(13) phosphorylation serves as a unique marker of stress and of small intestinal goblet cells
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS