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FLASH GENE
Symbol KRR1 contributors: np - updated : 22-07-2003
HGNC name KRR1, small subunit (SSU) processome component, homolog (yeast)
HGNC id 5176
Location 12q21.1      Physical location : 75.891.420 - 75.905.418
Synonym name
  • KRR1 small subunit processome component homolog
  • Rev interacting protein
  • HIV-1 rev binding protein 2
  • Synonym symbol(s) RIP-1, HRB2
    DNA
    TYPE functioning gene
    STRUCTURE 13.00 kb     2 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 3357 43 381 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Muscularstriatumskeletal  
    cell lineage
    cell lines lung cancer
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    RNA binding domain
    HOMOLOGY
    interspecies ortholog to murine Hrb2
    homolog to Drosophila dbe
    homolog to C.elegans C05C8.2
    homolog to yeast S.cerevisiae Krr1p
    Homologene
    FAMILY
  • KH family
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • may be required for cell division
  • CELLULAR PROCESS cell cycle, division
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • binding to GR-II, rev(HIV-1 protein), vpr (HIV-1 protein)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS