Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | KMT2B | contributors: mct/npt - updated : 02-01-2017 |
HGNC name | lysine methyltransferase 2B |
HGNC id | 15840 |
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Corresponding disease |
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Location | 19q13.11 Physical location : - | ||
Genatlas name | myeloid/lymphoid or mixed-lineage leukemia 4 | ||
Synonym name | |||
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Synonym symbol(s) | KIAA0304, MLL2, HRX2, TRX2, WBP7, MLL4, MLL1B, WBP-7, CXXC10 | ||
EC.number | 2.1.1.43 |
DNA |
TYPE | functioning gene |
STRUCTURE | 20.86 kb 37 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
Map | cen - UPK1A - TYMSL - ZNF145L - MLL4 - U2AF1L4 - CRYABL - CHN1L - PRODH2 - NPHS1 NPHS1 - APLP1 - qter |
Authors | Fitzgerald (99) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains | |
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HOMOLOGY |
interspecies | homolog to Drosophila trithorax hrx |
intraspecies | homolog to MLL gene chromosome 11 |
Homologene |
FAMILY | |
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CATEGORY | regulatory , transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,nucleoplasm |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, transcription, regulation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | DYT28 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |