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FLASH GENE
Symbol KLHL8 contributors: - updated : 02-12-2005
HGNC name kelch-like 8 (Drosophila)
HGNC id 18644
Location 4q22.1      Physical location : 88.082.213 - 88.141.674
Synonym symbol(s) KIAA1378
DNA
TYPE functioning gene
STRUCTURE 59.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrinepancreas    
Reproductivemale systemprostate   
Respiratorylung    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a BTB/POZ domain
  • six Kelch repeat motis
    • HOMOLOGY
    interspecies ortholog to murine Klhl8
    homolog to rattus Rn.6788
    homolog to C.elegans W02G9.2
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS