basic FUNCTION
| GC box binding protein, selectively activating mRNA synthesis from genes containing tandem repeats of GC boxes but repressing genes with a single GC box, like CYP1A1 |
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playing a role in the autoinduction of thyroid hormone receptor beta |
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necessary for late-phase maturation of dentate granule neurons both in dentate gyrus development and during adult hippocampal neurogenesis |
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may be involved in the carcinogenesis of human colorectal cancer |
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key pro-adipogenic transcription factor through regulation of PPARG expression with CEBPA at the middle stage of adipogenesis |
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is a transcriptional target of thyroid hormone T3 in some neuronal cell types and is involved in the developmental loss of regenerative ability of retinal ganglion cells |
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circadian transcription factor, that is substantially up-regulated in a cortisol and differentiation-state-dependent manner |
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affects potentially keratinocyte proliferation/differentiation by controlling the expression of target genes in a daytime-dependent manner |
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cell autonomous circadian clock in epidermis with a role of KLF9 for rhythmic modulation of target genes and with implications for dermatological homeostasis and disease |
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functions as clock output gene rather than being part of the core clock machinery |
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reduces the capacity of Purkinje cells (PC) to regenerate their axons |
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the physiological T3 burst in mammals is involved in the developmental loss of PC axon regenerative capacity |
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might be a key molecule involved in turning off the phase of Purkinje programmed cell death (PCD) |