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FLASH GENE
Symbol KIF27 contributors: - updated : 26-03-2005
HGNC name kinesin family member 27
HGNC id 18632
Location 9q22.1      Physical location : 86.451.616 - 86.536.342
Synonym symbol(s) COS2B
DNA
TYPE functioning gene
STRUCTURE 85.00 kb     20 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
TLE1 19p13.3 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) LOC392355 9 similar to ORF2 FLJ43950 9q21.33 FLJ43950 protein LOC389761 9 similar to RIKEN cDNA 1700013B16 LOC389762 9 hypothetical gene supported by AK126070 LOC389763 9 similar to RIKEN cDNA 1700013B16 LOC286228 9q21.33 similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; DEAD box-10 LOC392356 9 similar to 40S ribosomal protein S2 LOC392357 9 hypothetical gene supported by AK094743 FLJ31614 9q21.33 hypothetical protein FLJ31614 MGC20553 LOC169505 9q21.33 similar to RIKEN cDNA 5133401N09 UBQLN1 9q21.2-q21.3 ubiquilin 1 GKAP42 9q22.1 protein kinase anchoring protein GKAP42 KIF27 9q22.1 kinesin family member 27 C9orf64 9q22.1 chromosome 9 open reading frame 64 HNRPK 9q21.32-q22.33 heterogeneous nuclear ribonucleoprotein K C9orf76 9q22.1 chromosome 9 open reading frame 76 SLC28A3 9q22.2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 NTRK2 9q22.1 neurotrophic tyrosine kinase, receptor, type 2 AGTPBP1 9q21.33 ATP/GTP binding protein 1 LOC389764 9 similar to kinesin family member 27 LOC389765 9 similar to kinesin family member 27 LOC138198 9q22.1 similar to prohibitin FLJ21613 9q22.1 corneal wound healing-related protein GOLPH2 9p24.1-q32 golgi phosphoprotein 2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to drosophila Costal-2
Homologene
FAMILY kinesin-like protein family. kinesin II subfamily.
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
intracellular,nucleus
basic FUNCTION
  • playing an important roles in intracellular transport of organelles and in cell division
  • implicated in Hedgehog pathway through the interaction with Smoothened (SMO), Fused (STK36) and microtubules
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SMO, STK36
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS