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FLASH GENE
Symbol KIF25 contributors: npt/ - updated : 02-10-2007
HGNC name kinesin family member 25
HGNC id 6390
Location 6q27      Physical location : 168.418.552 - 168.445.769
Synonym name kinesin-like 3
Synonym symbol(s) KNSL3, MGC163361
DNA
TYPE functioning gene
STRUCTURE 27.22 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text four alternatively spliced isoforms in relative amount different in each tissue (Okamoto)
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1510 40.7 384 - Okamoto
  • full length isoform
  • containing exon 8
  • - splicing 1354 35.1 332 - Okamoto
    lacking exon 8
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N terminal globular domain
  • the motor domain with an ATP and the microtubule bindding sites
  • a long alpa-helical coiled-coil region (stalk region), involved in dimerization
  • a small C terminal domain, potentially involved in interaction with other proteins, vesicles or organelles
  • HOMOLOGY
    Homologene
    FAMILY
  • kinesin-like protein family
  • family of microtubule-associated motor proteins
  • CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • transporting organelles within cells and move chromosomes during cell division
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS