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FLASH GENE
Symbol KIF13A contributors: npt/ - updated : 17-12-2003
HGNC name kinesin family member 13A
HGNC id 14566
Location 6p23      Physical location : 17.760.584 - 17.987.799
Synonym name
  • homolog of mouse KIF13A mannose-6-phosphate receptor transporter
  • kinesin-like protein RBKIN
  • Synonym symbol(s) RBKIN, bA500C11.2, FLJ27232
    DNA
    TYPE functioning gene
    STRUCTURE 227.21 kb     38 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence cytosine-phosphate-guanine/HTF
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 5740 - 1749 - Jamain
    lack of exon 37
    - - 5110 - 1757 heart, skeletal muscle, fetal muscle Jamain
    lack of exon 36
    - - 4690 - 659 keart, skeletal muscle, fetal muscle Jamain
    lack of exon36-37
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveintestinelarge intestinecolon  
    Endocrinepancreas    
    Nervousbrain   highly
    Reproductivemale systemprostate   
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines retinoblastoma cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text kidney, placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N terminus with motor and stalk domain
  • consensus ATP/GTP binding site
  • variable C terminal domain
  • HOMOLOGY
    interspecies homolog to kif13a mannose 6 phosphate receptor transporter
    ortholog to Drosophila kinesin 73
    Homologene
    FAMILY
  • kinesin-like protein family
  • CATEGORY protooncogene , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    intracellular,nucleus
    basic FUNCTION
  • involved in the transport of specific synaptic vesicles
  • contributing to malignant progression of retinoblastoma
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cell to cell transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS