Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

KHDRBS2

contributors: mct/npt - updated : 28-05-2008

HGNC name	KH domain containing, RNA binding, signal transduction associated 2
HGNC id	18114

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6q11.1      Physical location : 62.389.864 - 62.996.100
Synonym name	Sam68-like mammalian protein 1
Synonym symbol(s)	SLM1, SLM-1, MGC26664, FLJ38664, bA535F17.1

DNA

TYPE	functioning gene
STRUCTURE	606.00 kb     9 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 9 - 2336 38.9 349 - Stoss (2004)

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid         Lymphoid/Immune spleen         Nervous brain

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a KH domain, which is embedded in a larger conserved domain called the STAR domain

HOMOLOGY

interspecies	homolog to rattus Slm1
	homolog to murine Khdrbs2

Homologene

FAMILY

STAR protein family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	may be having nucleic acid binding activity
	regulate actin organization, and is also necessary for normal sphingolipid metabolism, at least in part through regulation of the calcium/calmodulin-dependent phosphatase calcineurin, which binds directly to both proteins

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA	RNA associated

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS