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FLASH GENE
Symbol KDM1B contributors: SGE/npt - updated : 17-10-2007
HGNC name lysine (K)-specific demethylase 1B
HGNC id 21577
Location 6p22.3      Physical location : 18.155.618 - 18.224.084
Synonym name
  • amine oxidase, flavin containing 1
  • chromosome 6 open reading frame 193
  • Synonym symbol(s) FLJ33898, FLJ34109, C6orf193, AOF1, dJ298J15.2, FLJ43328, LSD2, DKFZp686I0412
    EC.number 1.-.-.-
    DNA
    TYPE functioning gene
    STRUCTURE 68.47 kb     18 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 3875 - 590 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine   highly
    Lymphoid/Immunelymph node   highly
    Urinarybladder   highly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductiveoocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a CW-type zinc finger
  • a SWIRM domain
  • HOMOLOGY
    Homologene
    FAMILY
  • flavin monoamine oxidase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having disulfide oxidoreductase activity
  • functioning as a H3K4 demethylase that is critical for establishing the DNA methylation imprints during oogenesis (Ciccone 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • FAD
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS