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FLASH GENE
Symbol KCNK15 contributors: mct/npt - updated : 08-02-2010
HGNC name potassium channel, subfamily K, member 15
HGNC id 13814
Location 20q13.12      Physical location : 43.374.487 - 43.379.666
Synonym name
  • two pore potassium channel KT3.3
  • TWIK-related acid-sensitive K(+) channel 5
  • acid-sensitive potassium channel protein TASK-5
  • potassium channel, subfamily K, member 14
    • Synonym symbol(s) KT3.3, TASK5, TASK-5, KIAA0237, KCNK11, KCNK14, K2p15.1, dJ781B1.1
    DNA
    TYPE functioning gene
    STRUCTURE 5.18 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 1286 36 330 - Karschin (2001)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivefemale systemovary   
     male systemtestis   
    Respiratorylung    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousmitral cell
    NervousPurkinje cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two pore-forming P domains
    • mono polymer heteromer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • two pore domain potassium channel family
    • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • may be having voltage-gated ion channel activity
  • may be playing a role in the transmission of temporal information in the auditory system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS