Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KAZALD1 contributors: - updated : 13-07-2006
HGNC name Kazal-type serine peptidase inhibitor domain 1
HGNC id 25460
Location 10q24.32      Physical location : 102.820.998 - 102.825.350
Synonym name
  • bone and odontoblast geene 1
  • Kazal-type serine protease inhibitor domain 1
  • Synonym symbol(s) FKSG40, FKSG28, BONO1, IGFBP-rP10, UNQ2945/PRO21184, bA108L7.1
    DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     5 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   highly
    Reproductivefemale systembreastmammary gland highly
     male systemprostate  highly
    Respiratoryrespiratory tracttrachea  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectivebone  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a Ig-like C2-type (immunoglobulin-like) domain
  • a IGFBP domain
  • a Kazal-like domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Kazald1 (84.2pc)
    homolog to rattus Kazald1 (85.2pc)
    Homologene
    FAMILY IGFBP superfamily
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION involved in the proliferation of osteoblasts during bone formation and bone regeneration
    CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS ossification
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by BMP2
    Other up-regulated at the early phase of bone regeneration
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS