protein
| acetylating SCL (TAL1) |
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CBP and p300 |
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activating HDAC13 |
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binding to TP73(coactivator for TP73-mediated transactivation |
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MYOD1 |
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interaction partner of ATF4 in leucine-starved cells |
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PTEN |
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directly interacts with CDK2 (this interaction is mainly produced during S and G(2)/M phases of the cell cycle) |
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KLF8 activation domain located between AAs 101-260 where the well-conserved Q118 and Q248 are essential for recruiting EP300 and KAT2B to activate target gene transcription |
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ESRRA interacts with and is acetylated by EP300 coactivator associated factor (KAT2B) |
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cooperates with EP300 and RUNX2 to mediate PTH activation of MMP13 transcription |
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induces CDKN1B degradation via proteasome |
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critical regulator of TP53-dependent CDKN1A expression in response to multiple TP53-activating stresses |
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selective influence of KAT2B on fear extinction is mediated, in part, by a transient recruitment of the repressive transcription factor ATF4 to the promoter of the immediate early gene EGR2, which competitively inhibits its expression |
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acts as a negative modulator of microtubule stability through acetylation of MAPRE1, a protein that controls the plus ends of microtubules |
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in mitosis, acetylates the mitotic checkpoint protein, BUB1B |
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directly binds to RUNX2 and acetylates RUNX2, leading to an increase in its transcriptional activity |
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HDAC3 regulates cyclin A stability by counteracting the action of the acetylases KAT2A/KAT2B |
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EP300 and KAT2B are two TRIM50 acetyltransferases and the balance between ubiquitination and acetylation regulates TRIM50 degradation |
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KAT2B and TADA3 regulate BID processing via PACS2, to modulate the mitochondrial cell death pathway in response to GZMB |
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KAT2A/KAT2B acetylation of PLK4 prevents centrosome amplification |