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FLASH GENE
Symbol IVNS1ABP contributors: - updated : 01-12-2005
HGNC name influenza virus NS1A binding protein
HGNC id 16951
Location 1q25.1-q31.1      Physical location : 185.265.523 - 185.286.461
Synonym symbol(s) NS1-BP, HSPC068, NS-1, KIAA0850, ND1, DKFZp686K06216
DNA
TYPE functioning gene
STRUCTURE 21.00 kb     14 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 4.205 71 642 - -
- - 4346 - 221 - -
an alternate exon causing a frameshift leading to a shorter isoform
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Reproductivefemale systemovary   
 male systemtestis   
Respiratorylung    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six kelch repeats
  • one BTB/POZ domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text located at nucleus in infected cells
    basic FUNCTION
  • involved in the repression of antioxidant response element-mediated detoxifying enzyme gene expression
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
    influenza virus NS1A binding protein
    protein interacting with the N-terminal regulatory domain of NFE2L2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS