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FLASH GENE
Symbol IPO9 contributors: - updated : 08-04-2004
HGNC name importin 9
HGNC id 19425
Location 1q31.3      Physical location : 201.798.287 - 201.853.421
Synonym symbol(s) Imp9, FLJ10402
DNA
TYPE functioning gene
STRUCTURE 47.00 kb     24 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
GPR25 1q32.1 G protein-coupled receptor 25 FLJ10901 1q32.1 hypothetical protein FLJ10901 KIF21B 1pter-q31.3 kinesin family member 21B CACNA1S 1q32 calcium channel, voltage-dependent, L type, alpha 1S subunit TMEM9 1q41 transmembrane protein 9 LOC388724 1 similar to hypothetical protein FLJ37794 DKFZp434B1231 1q32.1 eEF1A2 binding protein PKP1 1q32 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) TNNT2 1q32 troponin T2, cardiac LAD1 1q25.1-q32.3 ladinin 1 TNNI1 1q31.3 troponin I, skeletal, slow PHLDA3 1q31.3-q32.1 pleckstrin homology-like domain, family A, member 3 CSRP1 1q32.1 cysteine and glycine-rich protein 1 LOC388725 1 similar to mKIAA1151 protein NAV1 1q32.1 neuron navigator 1 IPO9 1q31.3 importin 9 LOC149345 LMOD1 1q32 leiomodin 1 (smooth muscle) TIMM17A 1q31.3-q32 translocase of inner mitochondrial membrane 17 homolog A (yeast) LOC391151 1 similar to 60S ribosomal protein L10 (QM protein homolog) RNPEP 1q32.1-q32.2 arginyl aminopeptidase (aminopeptidase B) ELF3 1q32.2 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) ET(B)R-LP-2 1q32.1 endothelin type b receptor-like protein 2 LOC127829 PTPN7 1q32.1 protein tyrosine phosphatase, non-receptor type 7 LOC388726 1 similar to osteotesticular protein tyrosine phosphatase LOC148713 1q32.1 similar to Osteotesticular phosphatase; protein tyrosine phosphatase, receptor type, V LGR6 1q32.1 leucine-rich repeat-containing G protein-coupled receptor 6 HSPC150 1q32.1 HSPC150 protein similar to ubiquitin-conjugating enzyme PPP1R12B 1q32.1 protein phosphatase 1, regulatory (inhibitor) subunit 12B HCP4 1q32.1 cytochrome c, somatic pseudogene SYT2 1q31.3 synaptotagmin II
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonamygdala  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one importin N-terminal domain
HOMOLOGY
Homologene
FAMILY importin beta family
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION mediates the nuclear import of H2B histone, RPS7 and RPL18A
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS cellular trafficking transport
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • binding to RPS7, RPL18A in a Ran-dependent manner
  • interacts with PPP2R1A, PPP2R1B
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS