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FLASH GENE
Symbol INTS9 contributors: npt - updated : 28-11-2005
HGNC name integrator complex subunit 9
HGNC id 25592
Location 8p21.1      Physical location : 28.625.175 - 28.747.698
Synonym name protein related to CPSF subunits of 74 kDa
Synonym symbol(s) FLJ10871, CPSF2L, RC-74, RC74, Int9
DNA
TYPE functioning gene
STRUCTURE 122.00 kb     17 Exon(s)
MAPPING cloned Y linked N status
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
17 - 2540 73 658 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer complex
HOMOLOGY
Homologene
FAMILY
  • RNA-metabolizing metallo-beta- lactamase-like family
  • INTS9 subfamily
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • is recruited to the U1 and U2 snRNA genes and mediates the snRNA's 3' end processing
  • the integrator complex mediates RNA polymerase-II-dependent transcription
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the RNA polymerase II complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • stably associated with RNAPII
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS