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FLASH GENE
Symbol INTS7 contributors: - updated : 28-11-2005
HGNC name integrator complex subunit 7
HGNC id 24484
Location 1p32.3      Physical location : 212.114.697 - 212.208.884
Synonym name
  • chromosome 1 open reading frame 73
  • INTS7 protein
  • Synonym symbol(s) INT7, C1orf73, DKFZP434B168
    DNA
    TYPE functioning gene
    STRUCTURE 94.00 kb     20 Exon(s)
    MAPPING cloned Y linked N status
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus    
     mouth    
    Lymphoid/Immunethymus   highly
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer complex
    HOMOLOGY
    interspecies ortholog to murine Ints7
    Homologene
    FAMILY multiprotein complex integrator family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • is recruited to the U1 and U2 snRNA genes and mediates the snRNA's 3' end processing
  • the integrator complex mediates RNA polymerase-II-dependent transcription
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the RNA polymerase II complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein stably associated with RNAPII
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS