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FLASH GENE
Symbol INO80E contributors: mct/npt - updated : 10-02-2009
HGNC name INO80 complex subunit E
HGNC id 26905
Location 16p11.2      Physical location : 30.007.530 - 30.017.112
Synonym name coiled-coil domain containing 95
Synonym symbol(s) CCDC95, FLJ90652, FLJ00079
DNA
TYPE like-sequence
STRUCTURE 9.58 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
Map pter - D16S321 - D16S2638 - INO80E - D16S2561E - D16S3225 - cen
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 1185 26.35 244 - Jin (2005)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • coiled-coil domain
  • HOMOLOGY
    Homologene
    FAMILY
  • SNF2 family of ATPases
  • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION
  • exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (Jin 2005)
  • functioning as an integral component of a multisubunit ATP-dependent chromatin remodeling complex (Conaway 2008)
  • contributes to a wide variety of chromatin-dependent nuclear transactions, including transcription, DNA repair and DNA replication (Conaway 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • ATP-dependent chromatin remodeling complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS