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FLASH GENE
Symbol INHBC contributors: npt/ - updated : 23-02-2004
HGNC name inhibin, beta C
HGNC id 6068
Location 12q13.1      Physical location : 57.828.542 - 57.844.609
Synonym name activin beta-C chain
Synonym symbol(s) IHBC
DNA
TYPE functioning gene
STRUCTURE 16.10 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 1990 36.4 352 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrineadrenal gland    
endocrinebraindiencephalonpituitary  
Nervousspinal cord    
Reproductivemale systemtestis   
 male systemprostate   
 ovary    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Nervouscentral   
cell lineage
cell lines benign prostatic hyerplasia cells
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , heteromer , dimer
isoforms Precursor
HOMOLOGY
interspecies homolog to murine Inhb
Homologene
FAMILY
  • TGFB superfamily member
  • BMP family
  • CATEGORY signaling hormone growth factor
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cells development and maturation, embryonic axial development
  • opposed function of activin
  • CELLULAR PROCESS cell life, differentiation
    cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal
    a component
  • forming heterodimers with INHBA, (AC), INHBB, (BC) of unknown function
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS