Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol INCA1 contributors: mct - updated : 04-03-2009
HGNC name inhibitor of CDK, cyclin A1 interacting protein 1
HGNC id 32224
Location 17p13.2      Physical location : 4.891.425 - 4.900.905
Synonym name
  • inhibitor of CDK interacting with cyclin A1
  • protein INCA1
  • Synonym symbol(s) HSD45, MGC148150, MGC148151
    DNA
    TYPE functioning gene
    STRUCTURE 9.48 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 1574 - 236 - 2004 15159402
    8 - 1404 - 221 -
    8 - 1287 - 236 - -
    8 - 1242 - 221 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis    Homo sapiens
    cell lineage
    cell lines bladder carcinoma cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • INCA family
  • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text C9orf9 and INCA1 were found to be co-localized principally in the cytoplasm
    basic FUNCTION
  • plays a role in several signaling pathways important for cell cycle control and meiosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • substrates for the cyclin A1-CDK2 kinase complex
  • interaction between C9orf9 and INCA1
  • ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS