protein
| CRB1, CRB2, MPP5, MPP6 |
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TJP3 can associate with INADL (INADL/TJP3 interaction is likely important for recruiting INADL and its associated proteins to tight junctions) |
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interaction partner of WWC1 (the last four AAs of WWC1 mediated binding to the eighth PDZ domain of INADL) |
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interacting with BAIAP2 ( |
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interacting with proteins involved in cytoskeletal dynamics (Alpi 2009) |
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interaction with MPDZ (INADL is indispensable for the establishment of tight junctions and epithelial polarization, whereas MPDZ is not) |
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AMOT directly binds the scaffolding proteins INADL and MPDZ and redistributes them and their binding partners from the plasma membrane to endosomes |
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interaction of TAZ with the multi-PDZ-containing PALS1-associated tight junction protein (INADL) |
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C terminus of PKD2 strongly interacts with PDZ domains 8-10 and to a weaker extent with PDZ domains 1-3 of INADL |
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MPDZ and INADL are closely related scaffold proteins and bind to many common interactors including MPP5 (protein associated with Lin seven) a member of the Crumbs complex |