Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IMPA1 | contributors: mct - updated : 16-01-2019 |
HGNC name | inositol(myo)-1(or 4)-monophosphatase 1 |
HGNC id | 6050 |
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Corresponding disease |
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Location | 8q21.13 Physical location : 82.569.150 - 82.598.589 | ||
Synonym name | |||
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Synonym symbol(s) | IMPA, MYOP, IMP | ||
EC.number | 3.1.3.25/ 3.1.3.94 |
DNA |
TYPE | functioning gene |
STRUCTURE | 29.44 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to C.elegans f13g3.5 |
intraspecies | homolog to IMPA2 |
Homologene |
FAMILY | inositol monophosphatase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | other |
signaling |
phosphate |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
magnesium Mg2+ |
protein |
cell & other |
REGULATION |
activated by | CALB1 |
inhibited by | by lithium, a drug used for the treatment of mood swings seen in bipolar disorder |
ASSOCIATED DISORDERS |
corresponding disease(s) | MRT59 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |