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FLASH GENE
Symbol IL4I1 contributors: npt/ - updated : 09-10-2007
HGNC name interleukin 4 induced 1
HGNC id 19094
Location 19q13.33      Physical location : 50.392.915 - 50.432.762
Synonym name Fig-1 protein
Synonym symbol(s) FIG1, LAAO, LAO
EC.number 1.4.3.2
DNA
TYPE functioning gene
STRUCTURE 39.85 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence cytosine-phosphate-guanine/HTF
Binding site   transcription factor
motif repetitive sequence   ALU
text structure STAT6 binding site,Ikaros,MZF-1 and STAT1 binding sites
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1798 62.9 567 spleen,thymus,tonsils,reactive lymph nodes,£lung,placenta,B cells,£primary mediastinal large B-cell lymphoma,highly Chavan
differing in the 5' end region
- splicing 2315 65.3 589 - Chavan
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide chain
  • four N glycosylation sites
  • three FAD binding sites
  • catalytic site
    • conjugated FlavoP , GlycoP
    isoforms Precursor
    HOMOLOGY
    interspecies ortholog to murine Il4i1
    Homologene
    FAMILY
  • flavin monoamine oxidase family
  • FIG1 subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    basic FUNCTION
  • having an L amino acid oxidase activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • FAD
    • protein
    cell & other
    REGULATION
    induced by IL4 in B lymphocytes
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS