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FLASH GENE
Symbol IL20RB contributors: mct - updated : 04-01-2013
HGNC name interleukin 20 receptor beta
HGNC id 6004
Location 3q22.3      Physical location : 136.676.706 - 136.729.920
Synonym name
  • fibronectin type III domain containing 6
  • interleukin-20 receptor II
  • Synonym symbol(s) MGC34923, FNDC6, DIRS1, IL-20R2
    DNA
    TYPE anonymous DNA segment
    STRUCTURE 53.22 kb     7 Exon(s)
    motif
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 2171 35 311 - 2012 22802649
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • fibronectin type III domain
  • HOMOLOGY
    Homologene
    FAMILY
  • type II cytokine receptor family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • IL20RA and IL10RB chains participate in forming the IL26 receptor
  • IL20RB signaling directly regulates CD8 and CD4 T cell answers, and down-regulates antigen-specific T cell responses
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to psoriasis
    Variant & Polymorphism SNP
  • haplotype significantly associated with psoriasis
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS