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FLASH GENE
Symbol IL1RL2 contributors: mct - updated : 24-11-2017
HGNC name interleukin 1 receptor-like 2
HGNC id 5999
Location 2q12      Physical location : 102.803.432 - 102.855.810
Synonym symbol(s) IL1RRP2
DNA
TYPE functioning gene
SPECIAL FEATURE arranged in tandem, component of a cluster
text tandemly arranged with I1R1,IL1R2,IL1RL1,IL18R2
STRUCTURE 52.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Map cen - D2S373 - IL1R2 - D2S1473 - IL1R1 - IL1RL2 - IL1RL1 - IL18R1 - D2S176 - qter
Authors Dale (99)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
TIR domain (Toll-interleukin1-resistance)
HOMOLOGY
interspecies homolog to murine Il1rl2
intraspecies homolog to interleukin 1 receptor protein 2
Homologene
FAMILY
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
ILR1L2 expression was significantly decreased in in Hirschsprung's disease (HSCR) specimens compared to controls
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS