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FLASH GENE
Symbol IL17REL contributors: mct/npt - updated : 03-06-2010
HGNC name interleukin 17 receptor E-like
HGNC id 33808
Location 22q13.33      Physical location : 50.432.941 - 50.451.055
Synonym name
  • IL-17 receptor E-like
  • putative interleukin-17 receptor E-like
    • Synonym symbol(s) FLJ41993
    DNA
    TYPE functioning gene
    STRUCTURE 18.11 kb     15 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    15 - 3635 - 336 - Albrecht (2010)
    EXPRESSION
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • likely, oligomerizes and binds specific IL17 cytokines (Franke 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to ulcerative colitis
    Variant & Polymorphism SNP rs5771069 strongly associated with ulcerative colitis (Franke 2010)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS