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FLASH GENE
Symbol IGHD contributors: npt - updated : 18-11-2005
HGNC name immunoglobulin heavy constant delta
HGNC id 5480
Location 14q32.33      Physical location : -
Synonym name
  • immunoglobulin delta
  • constant region of heavy chain of IgD
    • Synonym symbol(s) FLJ00382, FLJ46727, MGC29633
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text member of the IGH constant genes cluster
    STRUCTURE 7.27 kb     1 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map see IGHC@
    Physical map
    ELK2P1 14q32.3 ELK2, member of ETS oncogene family, pseudogene 1 MGC27165 14q32.33 hypothetical protein MGC27165 IGHG3 14q32.33 immunoglobulin heavy constant gamma 3 (G3m marker) IGHD 14q32.33 immunoglobulin heavy constant delta IGHM 14q32.33 immunoglobulin heavy constant mu
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneB cell
    cell lineage
    cell lines
    fluid/secretion serum
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three Ig domains with an hinge region between C1 and C2
    • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to C.elegans t28f12.3
    Homologene
    FAMILY
  • Ig superfamily
    • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    basic FUNCTION
  • involved in antigen induced lymphocyte differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
  • forming an homodimer of two D heavy chains bound by an unique disulfide bond
  • each heavy chain is bound to a light chain (kappa or lambda)
  • the N terminus of the heavy chain is bound to a V segment
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS