Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IGF2BP2 | contributors: mct - updated : 16-02-2011 |
HGNC name | insulin-like growth factor 2 mRNA binding protein 2 |
HGNC id | 28867 |
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Location | 3q27.2 Physical location : 185.361.527 - 185.542.827 |
Synonym name | |
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Synonym symbol(s) | p62, IMP2, VICKZ2, IMP-2 |
DNA |
TYPE | functioning gene |
STRUCTURE | 181.30 kb |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | enzyme , regulatory , RNA associated |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic | |
intracellular,nucleus |
basic FUNCTION | |
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CELLULAR PROCESS | protein, translation regulation |
PHYSIOLOGICAL PROCESS | development |
text | morphogenesis |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA | binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to type 2 diabetes (T2DM), and gestational diabetes |
Variant & Polymorphism SNP | IGF2BP2 rs1470579 and rs4402960 polymorphisms may be associated with the development of T2DM |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |