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FLASH GENE
Symbol IFNA2 contributors: mct - updated : 30-05-2013
HGNC name interferon, alpha 2
HGNC id 5423
Location 9p22      Physical location : 21.384.254 - 21.385.396
Synonym symbol(s) INFA2, IFNA
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 1.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Map see IFN1@
Physical map
IFNA21 9p22 interferon, alpha 21 LOC392289 9 similar to Interferon omega-1 precursor (Interferon alpha-II-1) IFNA4 9p22 interferon, alpha 4 LOC392290 9 similar to Interferon omega-1 precursor (Interferon alpha-II-1) IFNA7 9p22 interferon, alpha 7 IFNA10 9p22 interferon, alpha 10 G13P1 9p22 interferon alpha-L pseudogene LOC392291 9 similar to Interferon omega-1 precursor (Interferon alpha-II-1) IFNA16 9p22 interferon, alpha 16 IFNA17 9p22 interferon, alpha 17 LOC392292 9 similar to Interferon omega-1 precursor (Interferon alpha-II-1) IFNA14 9p22 interferon, alpha 14 IFNAP22 9p21 interferon, alpha pseudogene 22 IFNA5 9p22 interferon, alpha 5 KIAA1354 9p22 KIAA1354 protein IFNA6 9p22 interferon, alpha 6 IFNA13 9p22 interferon, alpha 13 IFNA2 9p22 interferon, alpha 2 IFNA8 9p22 interferon, alpha 8 LOC392293 9 similar to Interferon omega-1 precursor (Interferon alpha-II-1) IFNA1 9p22 interferon, alpha 1 LOC392294 9 similar to interferon-alpha
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to C.elegans y54g2a.t
Homologene
FAMILY interferon alpha,beta and delta family
CATEGORY immunity/defense
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • IFNL1, and IFNA2 differ in their ability to modulate IL12 production by TLR-activated macrophages and exhibit differential regulation of the IFNGR1 expression
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS