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FLASH GENE
Symbol IDI2 contributors: mct - updated : 28-01-2009
HGNC name isopentenyl-diphosphate delta isomerase 2
HGNC id 23487
Location 10p15.3      Physical location : 1.064.846 - 1.071.799
Synonym name
  • diphosphate dimethylallyl diphosphate isomerase 2
  • IPP isomerase 2
  • isopentenyl pyrophosphate isomerase 2
  • Synonym symbol(s) IPPI2
    EC.number 5.3.3.2
    DNA
    TYPE functioning gene
    STRUCTURE 6.95 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1359 26.62 227 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal specific Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • NUDIX domain
  • HOMOLOGY
    Homologene
    FAMILY
  • IPP isomerase type 1 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • has the ability to catalyze the isomerization of [(14)C]IPP to [(14)C]DMAPP
  • may be involved in the specialized production of isoprenyl diphosphates for the posttranslational modification of proteins
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • Mg2+
  • protein
    cell & other
    REGULATION
    Other regulated independently from IDI1, by a mechanism that may involve PPARA
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS