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FLASH GENE
Symbol IDI1 contributors: mct/npt - updated : 16-01-2009
HGNC name isopentenyl-diphosphate delta isomerase 1
HGNC id 5387
Location 10p15.3      Physical location : 1.085.965 - 1.095.061
Synonym name
  • dimethylally/disphosphate isomerase
  • IPP isomerase
  • isopentenyl pyrophosphate isomerase 1
  • Synonym symbol(s) IPPI1, IPP1
    EC.number 5.3.3.2
    DNA
    TYPE functioning gene
    STRUCTURE 9.10 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map pter - D10S588 - D10S1280E - IDI1 - D10S1388E - D10S486E - cen
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 2150 - 284 - Breitling (2003)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary gland   highly
    Endocrineadrenal gland   highly
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • Mut T-like domain
  • C terminal peroxisomal targeting sequence
  • HOMOLOGY
    interspecies homolog to C.elegans F09C6.1
    Homologene
    FAMILY
  • IPP isomerase type 1 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP) (Breitling 2003)
  • responsible for housekeeping isomerase activity (Breitling 2003)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    cholesterol
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS