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FLASH GENE
Symbol HYAL3 contributors: - updated : 13-02-2004
HGNC name hyaluronoglucosaminidase 3
HGNC id 5322
Location 3p21.3      Physical location : 50.330.261 - 50.336.899
Synonym name hyaluronidase 3
Synonym symbol(s) LUCA3, LUCA14, MINNA14
EC.number 3.2.1.35
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text clustered with HYAL1 and HYAL2
STRUCTURE 6.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
cell lineage
cell lines
fluid/secretion secreted in the sperm
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an EGF-like domain
HOMOLOGY
interspecies homolog to murine Hyal3
Homologene
FAMILY glycosyl hydrolase 56 family
CATEGORY enzyme , tumor suppressor
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • secreted in the sperm and involved in fertilization
  • involved in glycosaminoglycan catabolism
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS