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FLASH GENE
Symbol HTATSF1 contributors: - updated : 06-04-2004
HGNC name HIV TAT specific factor 1
HGNC id 5276
Location Xq26-Xq27      Physical location : 135.579.237 - 135.594.501
Synonym name cofactor required for Tat activation of HIV-1 transcription
Synonym symbol(s) TAT-SF1, dJ196E23.2
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC340581 Xq26.3 hypothetical protein LOC340581 LOC392545 X similar to high mobility group protein homolog HMG4 LOC389887 X similar to RIKEN cDNA 1110012O05 CXX1 Xq26 CAAX box 1 DKFZP564B147 Xq26.3 DKFZP564B147 protein LOC159049 Xq26.3 hypothetical LOC159049 FLJ20527 Xq26.3 hypothetical protein FLJ20527 LOC392546 X similar to hypothetical protein FLJ20527 LOC389888 X similar to hypothetical protein FLJ20527 LOC389889 X hypothetical gene supported by BC061642 ZNF75 Xq26 zinc finger protein 75 (D8C6) FLJ23614 Xq26.3 hypothetical protein FLJ23614 LOC392547 X similar to KIAA0445 protein LOC203522 Xq26.3 hypothetical protein LOC203522 LOC392548 X similar to C-ets-2 protein LOC139587 Xq26.3 similar to sarcoma antigen; putative tumor antigen MGC27005 Xq26.3 hypothetical protein MGC27005 SAGE Xq28 hypothetical protein MGC27005 LOC93380 Xq26.3 hypothetical protein LOC93380 SLC9A6 Xq26.3 solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 LOC392549 X similar to Glyceraldehyde 3-phosphate dehydrogenase, liver (GAPDH) LOC139542 Xq26.3 similar to E2F transcription factor 6 isoform a FHL1 Xq26 four and a half LIM domains 1 FLJ12649 Xq26.3 hypothetical protein FLJ12649 GPR112 Xq26.3 G protein-coupled receptor 112 BRS3 Xq26-q28 bombesin-like receptor 3 HTATSF1 Xq26-Xq27 HIV TAT specific factor 1 VGLL1 Xq26.3 vestigial like 1 (Drosophila) TNFSF5 Xq26 tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) ARHGEF6 Xq26 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 LOC392550 X similar to ribosomal protein L7 LOC392551 X similar to Ras-related protein Rab-28 (Rab-26) RBMX Xq26 RNA binding motif protein, X chromosome LOC389890 X hypothetical gene supported by AF419855; NM_005839 LOC389891 X similar to ENSANGP00000013187 GPR101 Xq25-27.1 G protein-coupled receptor 101 LOC286472 Xq26.3 similar to Ras-related C3 botulinum toxin substrate homolog DJ20J23.1 ZIC3 Xq26.2 Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) LOC389892 X similar to Mothers against decapentaplegic homolog interacting protein (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
two RNA recognition motifs
conjugated PhosphoP
HOMOLOGY
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION may mediate a broadly active cellular process in addition to its role of transcriptional elongation regulator in TAT activation
CELLULAR PROCESS nucleotide, transcription, regulation
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA interacts with trans-acting responsive (TAR) element of RNA pol II
small molecule
protein
  • interacts with snRNPs to stimulate transcriptional elongation and mRNA splicing
  • interacts with P-TEFb
  • cell & other
    REGULATION
    Other phosphorylated by P-TEFb
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS