protein
| binding DNAJC13 through its DnaJ domain |
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binds to the microtubule-binding domain of tau, without an absolute requirement for tau phosphorylation |
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formation of a stable complex between chaperonin-containing TCP1 and HSPA8, two eukaryotic representatives of these chaperone families |
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direct binding between the N-terminus and the third cytoplasmic loop of SLC18A2, as well as, a region containing the substrate binding and the C-terminal domains of HSPA8 |
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interaction between the head domain of KRT5 and HSPA8, a chaperone also involved in vesicle uncoating (this interaction is involved in melanosome formation or transport in keratinocytes) |
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interacts with both CDKN1C and CDKN1B and the subcellular localization of HSPA8 was critical to maintain HSC (hematopoietic stem cell) cycle kinetics |
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DNAJB6 binds HSPA8 and causes dephosphorylation of GSK3B at Ser 9 by recruiting protein phosphatase, PPP2CA |
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HSPA8 is a prerequisite for the surface translocation and angiogenic function of NCL, which suggests strategies to target both HSPA8 and NCL for more effective antiangiogenic therapies |
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is a potential interacting protein of MAPK1 |
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plays a key role in CALM1-dependent nuclear import of SRY |
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dynamic C-terminal region of HSPA8 provides for flexibility between STUB1 and the chaperone |
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recruits PPP5C and activates its phosphatase activity which suggests dual roles for PPP5C that might link chaperone systems with signaling pathways in cancer and development |
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HSPA8 interacted with RAB1A in a chaperone-dependent manner |
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BBC3 associates with HSPA8/HSC70 (heat shock 70kDa protein 8), leading to its lysosome translocation and uptake |
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critical role of HSPA8 in SV40 ER-to-cytosol penetration and SGTA controls HSPA8 to impact this process |
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GKN2 promotes oxidative stress-induced gastric cancer cell apoptosis via the HSPA8 pathway |
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DNAJA2 and DNAJA1 were both important for CFTR folding, however overexpressing DNAJA2 but not DNAJA1 enhanced CFTR degradation at the endoplasmic reticulum by HSPA4/HSPA8 and the E3 ubiquitin ligase STUB1 |