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FLASH GENE
Symbol HSPA12B contributors: - updated : 05-01-2006
HGNC name heat shock 70kD protein 12B
HGNC id 16193
Location 20p13      Physical location : 3.713.355 - 3.733.756
Synonym name chromosome 20 open reading frame 60
Synonym symbol(s) FLJ32150, dJ1009E24.2, C20orf60
DNA
TYPE functioning gene
STRUCTURE 20.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
AVP 20p13 arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) UBCE7IP5 20p13 likely ortholog of mouse ubiquitin conjugating enzyme 7 interacting protein 5 FLJ13149 20p13 hypothetical protein FLJ13149 ProSAPiP1 20p13 ProSAPiP1 protein C20orf116 20p13 chromosome 20 open reading frame 116 ITPA 20p inosine triphosphatase (nucleoside triphosphate pyrophosphatase) SLC4A11 20p12 solute carrier family 4, sodium bicarbonate transporter-like, member 11 C20orf194 20p13 chromosome 20 open reading frame 194 UBE2V1P1 20p13 ubiquitin-conjugating enzyme E2 variant 1 pseudogene 1 ATRN 20p13 attractin SF3A3P 20p13 splicing factor 3a, subunit 3 pseudogene GFRA4 20p13-p12 GDNF family receptor alpha 4 ADAM33 20p13 a disintegrin and metalloproteinase domain 33 SN 20p13 sialoadhesin HSPA12B 20p13 heat shock 70kD protein 12B C20orf27 20p13 chromosome 20 open reading frame 27 C20orf28 20pter-q11.23 chromosome 20 open reading frame 28 CENPB 20p13 centromere protein B, 80kDa CDC25B 20p13 cell division cycle 25B C20orf29 20p13 chromosome 20 open reading frame 29 KIAA1271 20p13 KIAA1271 protein PANK2 20p13 pantothenate kinase 2 (Hallervorden-Spatz syndrome) RNF24 20p13-p12.1 ring finger protein 24 LOC388783 20 similar to hypothetical protein RPL21P2 20p13 ribosomal protein L21 pseudogene 2 MGC34919 20p13 hypothetical protein MGC34919 SMOX 20p13 spermine oxidase ADRA1D 20p13 adrenergic, alpha-1D-, receptor
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Lymphoid/Immunespleen    
Nervousgangliasensory gangliadorsal root  
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebonesubchondral  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an atypical heat shock protein 70 (Hsp70) ATPase domain
HOMOLOGY
Homologene
FAMILY distant member of the mammalian Hsp70 family
CATEGORY chaperone/stress
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION may be involved in susceptibility to atherosclerosis
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule nucleotide,
ATP
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in atherosclerosis
Susceptibility atherosclerosis
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS