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FLASH GENE
Symbol HSPA12B contributors: - updated : 05-01-2006
HGNC name heat shock 70kD protein 12B
HGNC id 16193
Location 20p13      Physical location : 3.713.355 - 3.733.756
Synonym name chromosome 20 open reading frame 60
Synonym symbol(s) FLJ32150, dJ1009E24.2, C20orf60
DNA
TYPE functioning gene
STRUCTURE 20.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Lymphoid/Immunespleen    
Nervousgangliasensory gangliadorsal root  
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebonesubchondral  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an atypical heat shock protein 70 (Hsp70) ATPase domain
HOMOLOGY
Homologene
FAMILY distant member of the mammalian Hsp70 family
CATEGORY chaperone/stress
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION may be involved in susceptibility to atherosclerosis
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule nucleotide,
ATP
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in atherosclerosis
Susceptibility atherosclerosis
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS