Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HSFY1 contributors: mct - updated : 30-11-2021
HGNC name heat shock transcription factor, Y-linked 1
HGNC id 18568
Location Yq11.222      Physical location : 20.708.573 - 20.935.604
Synonym name heat shock transcription factor 2-like
Synonym symbol(s) HSF2L, HSFY
DNA
TYPE functioning gene
STRUCTURE 59.29 kb     7 Exon(s)    two Copie(s)
text structure two identical and functional full-length copies of HSFY map in palindrome P4 of AZFb
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 splicing 1395 45.1 401 present in many tissues including testis and ejaculated sperm 2004 15044259
2 splicing 1058 23.4 203 testis-specific 2004 15044259
- splicing 1476 - 214 testis-specific 2004 15044259
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific Homo sapiens
 male systemmale genital tractepididymis   Mus musculus
cells
SystemCellPubmedSpeciesStageRna symbol
ReproductiveSertoli cell Homo sapiens
Reproductivespermatogonia
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • DNA binding domain
  • an HSF domain typical of HSF proteins
  • HOMOLOGY
    Homologene
    FAMILY heat shock factor family
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in transcription regulation
  • implicated in spermatogenesis
  • exhibits a stage-dependent translocation from the cytoplasm to the nucleus in spermatogenetic cells during spermatogenesis =
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS