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FLASH GENE
Symbol HSBP1 contributors: - updated : 24-01-2005
HGNC name heat shock factor binding protein 1
HGNC id 5203
Location 16q23.3      Physical location : 83.841.592 - 83.846.594
Synonym symbol(s) NPC-A-13
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text cord blood
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two potential hydrophobic repeats, which are essential for the interaction of HSF1 and HSBP1
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a role as a negative regulator of heat shock response
  • may have a role in the suppression of the activation of the stress reponse during the aging process
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds to heat shock factor 1(HSF1)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS